The Biomedical Imaging research team aims at developing optical methods for tissue diagnostics using microscopic and spectroscopic techniques. This goal is achieved by using laser microscopy for applications involving tissue diagnostics and pathological assessment, and by using fiber-probe multimodal spectroscopy approach for clinical applications. Thes methods are applied to a broad range of tissues in collaboration with medical experts.
In single molecule biophysics we are working both on in-vitro and in-vivo systems by using manipulation strategies based both on fast and high sensitive optical manipulation coupled to single molecule detection with high sensitivity and co-localisation accuracy.
We are applying several advanced optical methodologies to provide novel insights on anatomical and functional properties of mouse and human brain at cellular resolution.
We are exploiting the advantages of state of the art genetic, cell biological, histochemical and imaging methodologies in cell typing, fibre orientation (“connectivity”) and protein distribution across brain regions.