The Neuroimaging Group develops and applies innovative optical technologies to explore brain structure and function. Novel implementations of light-sheet microscopy are applied to resolve neuronal anatomy in whole fixed mouse brains with cellular resolution and the dynamics of neuronal activity across the whole brain of live zebrafish larvae. The plasticity of the injured brain is dissected through cutting-edge optical methods, where the dynamics of brain rewiring are monitored in terms of structural remodelling and functional remapping. Finally, cutting-edge clearing and staining methods are developed to investigate the three-dimensional molecular and cellular architecture of large human brain samples.
The main topics addressed by the Neuroimaging Group are the following: